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A GLP-1 protocol's first 90 days

What actually happens month by month, what to eat, and the mistake that costs most women their lean mass.

Month one: appetite, not the scale

The first thing that changes is not your weight — it is the volume of the conversation you have been having with food. Most people describe it as the noise going quiet. Portions get smaller without effort, and the mid-afternoon negotiation simply stops happening.

Start at the lowest sensible dose. Almost every account of a miserable first month traces back to starting too high, and the gastrointestinal effects that follow are dose-related, not inevitable.

Month two: the lean mass problem

Here is the part that gets under-discussed. When you lose weight rapidly, a meaningful proportion of what you lose can be muscle — and losing muscle lowers your resting metabolic rate, which makes maintaining the result harder later.

Two things protect against it: protein intake and resistance training. Aim for meaningfully more protein than feels necessary, which is difficult precisely because your appetite is suppressed. This is the tension at the centre of the whole protocol, and planning for it is the difference between a result that holds and one that does not.

Month three: deciding what happens next

By month three you should have enough information to make a real decision rather than a hopeful one. Is the rate sustainable? Is lean mass holding? Is the dose still right, or have you titrated past the point of useful return?

The exit strategy matters as much as the entry. Appetite signalling returns when you stop, and if nothing else has changed in the meantime, so does the weight. The protocol buys you a window in which building different habits is unusually easy. Using that window is the actual work.

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